Min Seob Lee Dr. Min Seob Lee is a founder and President of Diagnomics, Inc. in San Diego California, and is currently taking a responsibility of Chief Executive Officer. Diagnomics is developing solutions for personalized medicine based on genome information utilizing advanced bioinformatics capability and diagnostic development.
Dr. Lee has extensive global experience in the life sciences business arena including bio-tech, pharmaceutical and diagnostics companies with expertise in personal genomics, pharmacogenomics, bioinformatics and molecular diagnostic. Prior to Diagnomics, he was a vice president of Theragen’s Bio Institute and the CTO of GenomeCare. He started as an entrepreneur by establishing Precision Biocount Inc, - a next generation diagnostics company located in San Diego (2009). Prior to this, he held several positions of increasing responsibility from 2005 to 2009 at Sequenom in San Diego within the Diagnostic Development Department and Center for Molecular Medicine. Sequenom is a successful company committed to providing the best genomic and genetic analysis solution for genome research and molecular diagnostics. Before Sequenom, Dr. Lee was in charge of a CLIA (Clinical Laboratory Improvement Amendments) molecular diagnostic laboratory performing high-throughput genome sequencing and genotyping at Genaissance Pharmaceuticals in Connecticut. Genaissance was acquired by Clinical Data, a bio-pharmaceutical company focuses on personalized therapeutics and diagnostics development from genomics. He also gained bioinformatics industry experience through his involvement with DoubleTwist Inc. in 2000.
Dr. Lee published numerous articles and has been granted several US and international patents in the area of personalized medicine, genomics and diagnostics. He conducted his post-doctoral fellowship at the Genomics and Proteomics Center at Harvard Medical School, and received a Ph.D. in Molecular Medicine from City of Hope National Medical Center of the Beckman Research Institute in California.
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References:
Edwards, DR, Lee, M.S., et al (2011) Polymorphisms in Maternal and Fetal Genes Encoding for Proteins Involved in Extracellular Matrix Metabolism Alter the Risk for Small-for-Gestational-Age, JMFNM;24(2):362.
Romero, R., Lee, M.S., et al. (2010) Identification of Fetal and Maternal Single Nucleotide Polymorphisms in Candidate Genes That Predispose to Preterm Prelabor Rupture of Membranes., AJOG;203(4) :361.
Romero, R., Lee, M.S., et al. (2010) : Identification of Fetal and Maternal Single Nucleotide Polymorphisms in Candidate Genes That Predispose to Spontaneous Preterm Labor with Intact Membranes., AJOG;202(5):431.
Tang, M., Lee M.S.,et al (2008) : Identification of RNA SNP markers for noninvasive prenatal diagnosis (NIPD) of Trisomy 18 and Trisomy 13. AJOG; 199(6):S163.
Goddard, K., Lee, M.S., et al. (2007) : Candidate-Gene Association Study of Mothers with Pre-Eclampsia, and Their Infants, Analyzing 775 SNPs in 190 Genes., Hum Hered ;63(1):16.
Lee, M.S., (2002) : Personalized Medicine From Genomics, KSEA 30(3): 29.
Stephens, J.C., Lee, M.S., et al. (2001): Haplotype Variation and Linkage Disequilibrium in 313 Human Genes. Science 293: 489.
Lee, M.S., Glackin, C.A., et.al. (2000): Cloning of Human Dermo-1 Family of Twist Basic HLH Transcription Factors: Importance for early bone development. Bone 27(5): 591.
Lee, M.S., Glackin C.A., et.al. (2000): Twist, a Basic HLH Transcription Factor, Can Regulate the Human Osteogenic Lineage. JCB. 75: 566.
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